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Rational Design of and Mechanism Insight into an Efficient Antifreeze Peptide for Cryopreservation

Haishan Qi,Yihang Gao,Lin Zhang,Zhongxin Cui,Xiaojie Sui,Jianfan Ma,Jing Yang,Zhiquan Shu,Lei Zhang,

Engineering doi: 10.1016/j.eng.2023.01.015

Abstract: The development of effective antifreeze peptides to control ice growth has attracted a significant amountwe propose a novel design method based on an in-depth investigation of repetitive motifs in various ice-bindingIn particular, a designed antifreeze peptide named AVD exhibits ideal ice recrystallization inhibitionMD) simulations indicated that the Thr6 and Asn8 residues of the AVD peptide are fundamental to its ice-bindingcapacity, while the Ser18 residue can synergistically enhance their interaction with ice, revealing

Keywords： Antifreeze peptides     Evolution analysis     Ice recrystallization inhibition     Molecular dynamics simulation    

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Microstructure investigation of dynamic recrystallization in hard machining: From thermodynamic irreversibility

Binxun LI, Xinzhi ZHANG, Song ZHANG

Frontiers of Mechanical Engineering 2021, Volume 16, Issue 2,   Pages 315-330 doi: 10.1007/s11465-020-0612-4

Abstract: The drastically changed thermal, mechanical, and chemical energies within the machined surface layer during hard machining tend to initiate microstructural alteration. In this paper, attention is paid to the introduction of thermodynamic potential to unravel the mechanism of microstructure evolution. First, the thermodynamic potential-based model expressed by the Helmholtz free energy was proposed for predicting the microstructure changes of serrated chip and the machined surface layer. Second, the proposed model was implemented into a validated finite element simulation model for cutting operation as a user-defined subroutine. In addition, the predicted irreversible thermodynamic state change in the deformation zones associated with grain size, which was reduced to less than 1 m from the initial size of 1.5 m on the machined surface, was provided for an in-depth explanation. The good consistency between the simulated results and experimental data validated the efficacy of the developed model. This research helps to provide further insight into the microstructure alteration during metal cutting.

Keywords： thermodynamic irreversibility     Helmholtz free energy     microstructure evolution     dynamic recrystallization    

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Chronic inhibition of cyclic guanosine monophosphate-specific phosphodiesterase 5 prevented cardiac fibrosisthrough inhibition of transforming growth factor β-induced Smad signaling

Wei Gong,Mengwen Yan,Junxiong Chen,Sandip Chaugai,Chen Chen,Daowen Wang

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 445-455 doi: 10.1007/s11684-014-0378-3

Abstract: PDE5 inhibition prevents cardiac fibrosis by reducing CBP1 recruitment to Smad transcriptional complexes

Keywords： PDE5     cardiac fibrosis     TGF-β     CREB    

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Numerical simulation on flow of ice slurry in horizontal straight tube

Shengchun LIU,Ming SONG,Ling HAO,Pengxiao WANG

Frontiers in Energy 2021, Volume 15, Issue 1,   Pages 201-207 doi: 10.1007/s11708-017-0451-0

Abstract: Numerical simulation on flow of ice slurry in horizontal straight tubes was conducted in this paper toThis paper determined the influence of the diameter and length of tubes, the ice packing factors (IPF) and the flow velocity of ice slurry on pressure loss by using numerical simulation, based on two-phaseIt could also be concluded that future rheological model of ice slurry should be considered in three

Keywords： ice slurry     horizontal tubes     numerical simulation     pressure drop     viscosity model    

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Application of Ice Pigging in a Drinking Water Distribution System: Impacts on Pipes and Bulk Water Quality

Yujing Huang,Zhiwei Chen,Guilin He,Yu Shao,Shuang Song,Feilong Dong,Tuqiao Zhang,

Engineering doi: 10.1016/j.eng.2023.09.016

Abstract: Ice pigging is an emerging technique for pipe cleaning in drinking water distribution systems.However, substantial confusion and controversy exist on the potential impacts of ice pigging on bulkThe microstructural and trace element characterization results showed that ice pigs would scarcely disturbThe bacterial richness and diversity of bulk water decreased significantly after ice pigging.concentrations, and the 15 most abundant taxa in bulk water, which could be used to guide practical ice

Keywords： Ice pigging     Pipe cleaning     Drinking water distribution system     Bacterial community     Sediments    

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Purification of ice structuring protein complexes from winter wheat using Triton X-114 phase partitioning

Huaneng XU, Haiying CHEN, Weining HUANG,

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 4,   Pages 383-385 doi: 10.1007/s11705-009-0249-7

Abstract: Ice structuring proteins (ISPs) isolated from the cold-acclimated plants have a great potential in improving

Keywords： separation technique     thermal hysteresis     cold-acclimated     purification     X-114    

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simultaneous anammox and denitrification system with short-term pyridine exposure: Process capability, inhibition

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1433-3

Abstract:

• Short-term effect of the pyridine exposure on the SAD process was investigated.

Keywords： Anammox     Inhibition     Metabolic pathway     Microbial community     Pyridine     SAD    

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ROOT EXUDATES FROM CANOLA EXHIBIT BIOLOGICAL NITRIFICATION INHIBITION AND ARE EFFECTIVE IN INHIBITING

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 2,   Pages 177-186 doi: 10.15302/J-FASE-2021421

Abstract: This biological nitrification inhibition (BNI) capacity can decrease N loss and increase N uptake fromRoot exudates were collected and their inhibition of the ammonia oxidizing bacterium, NitrosospiraSubsequent pot experiments were used to test the inhibition of native nitrifying communities in soil.The level of nitrification inhibition across the three cultivars was similar to the well-studied high-BNI

Keywords： ammonia oxidizing microorganisms / biological nitrification inhibition / farming rotations / nitrogen    

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Inhibition character of crotonaldehyde manufacture wastewater on biological acidification

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1403-9

Abstract:

• The inhibition of the main organic pollutions in CMW was demonstrated

Keywords： Crotonaldehyde manufacture wastewater     Biological acidification     Volatile fatty acids     Inhibition     Toxic    

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Roles of integrin β3 cytoplasmic tail in bidirectional signal transduction in a trans-dominant inhibition

Jiansong Huang,Yulan Zhou,Xiaoyu Su,Yuanjing Lyu,Lanlan Tao,Xiaofeng Shi,Ping Liu,Zhangbiao Long,Zheng Ruan,Bing Xiao,Wenda Xi,Quansheng Zhou,Jianhua Mao,Xiaodong Xi

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 311-319 doi: 10.1007/s11684-016-0460-0

Abstract: beta;3 cytoplasmic tail in integrin αIIbβ3 bidirectional signaling using a trans-dominant inhibition

Keywords： integrin β3     signal transduction     trans-dominant inhibition model    

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Head-to-tail cyclization of a heptapeptide eliminates its cytotoxicity and significantly increases its inhibition

Shuai Ma, Huan Zhang, Xiaoyan Dong, Linling Yu, Jie Zheng, Yan Sun

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 2,   Pages 283-295 doi: 10.1007/s11705-017-1687-2

Abstract: Inhibition of A fibrillation is thus a promising therapeutic approach to the prevention and treatment

Keywords： Alzheimer’s disease     amyloid β-protein     cyclic peptide     inhibition     protein aggregation    

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Ice hazard on the grid analysis of disaster and emergency power grid construction of the platform

Zhu Youliang,Liang Wen​​​​​​​,Yang Jihai,Tao Zhenwen​​​​​​​,Ma Yong,Liu Xianming

Strategic Study of CAE 2010, Volume 12, Issue 3,   Pages 61-67

Abstract:

The expense of jiangxi province in the ice disaster all around our country

Keywords： power grid     ice disaster     emergency management    

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Effects of galectin-3 inhibition on endometrial cell cycle and adhesion

LEI Caixia, ZHANG Wei, SUN Xiaowei, DU Guoping, WANG Li, LIU Yinkun

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 390-397 doi: 10.1007/s11684-007-0076-5

Abstract: Inhibition of gal-3 expression decreased S-phase but increased G1 phase cells.
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Model test study for ice force on the bank-head of the lead-navigating bank

SONG An, SUN Jinliang, LU Hai, WANG Yi′an

Frontiers of Structural and Civil Engineering 2007, Volume 1, Issue 2,   Pages 222-228 doi: 10.1007/s11709-007-0027-x

Abstract: To determine the bank-head s ice force of the lead-navigating bank at key position that faces the icevelocity on the ice force , ratio of components of forces when ice sheet acting on the vertical bank-head, ice force ratio of vertical to 45?incline as well as ratio of level ice force to the vertical ice force when acting on 45? incline.the result calculated by the present formula of ice force and the experimental results.

Keywords： comparison     lead-navigating bank     vertical bank-head     certain     Preliminary    

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Comparison in executive function in Chinese preterm and full-term infants at eight months

Yao Feng, Hong Zhou, Yan Zhang, Anthony Perkins, Yan Wang, Jing Sun

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 164-173 doi: 10.1007/s11684-017-0540-9

Abstract: infants, the preterm infants performed more poorly on all measures of EF including working memory, inhibitionto prepotent responses, inhibition to distraction, and planning, and the differences remained after

Keywords： executive function (EF)     preterm infant     working memory     inhibition to prepotent response     inhibition to    

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Title Author Date Type Operation

Rational Design of and Mechanism Insight into an Efficient Antifreeze Peptide for Cryopreservation

Haishan Qi,Yihang Gao,Lin Zhang,Zhongxin Cui,Xiaojie Sui,Jianfan Ma,Jing Yang,Zhiquan Shu,Lei Zhang,

Journal Article

Microstructure investigation of dynamic recrystallization in hard machining: From thermodynamic irreversibility

Binxun LI, Xinzhi ZHANG, Song ZHANG

Journal Article

Chronic inhibition of cyclic guanosine monophosphate-specific phosphodiesterase 5 prevented cardiac fibrosisthrough inhibition of transforming growth factor β-induced Smad signaling

Wei Gong,Mengwen Yan,Junxiong Chen,Sandip Chaugai,Chen Chen,Daowen Wang

Journal Article

Numerical simulation on flow of ice slurry in horizontal straight tube

Shengchun LIU,Ming SONG,Ling HAO,Pengxiao WANG

Journal Article

Application of Ice Pigging in a Drinking Water Distribution System: Impacts on Pipes and Bulk Water Quality

Yujing Huang,Zhiwei Chen,Guilin He,Yu Shao,Shuang Song,Feilong Dong,Tuqiao Zhang,

Journal Article

Purification of ice structuring protein complexes from winter wheat using Triton X-114 phase partitioning

Huaneng XU, Haiying CHEN, Weining HUANG,

Journal Article

simultaneous anammox and denitrification system with short-term pyridine exposure: Process capability, inhibition

Journal Article

ROOT EXUDATES FROM CANOLA EXHIBIT BIOLOGICAL NITRIFICATION INHIBITION AND ARE EFFECTIVE IN INHIBITING

Journal Article

Inhibition character of crotonaldehyde manufacture wastewater on biological acidification

Journal Article

Roles of integrin β3 cytoplasmic tail in bidirectional signal transduction in a trans-dominant inhibition

Jiansong Huang,Yulan Zhou,Xiaoyu Su,Yuanjing Lyu,Lanlan Tao,Xiaofeng Shi,Ping Liu,Zhangbiao Long,Zheng Ruan,Bing Xiao,Wenda Xi,Quansheng Zhou,Jianhua Mao,Xiaodong Xi

Journal Article

Head-to-tail cyclization of a heptapeptide eliminates its cytotoxicity and significantly increases its inhibition

Shuai Ma, Huan Zhang, Xiaoyan Dong, Linling Yu, Jie Zheng, Yan Sun

Journal Article

Ice hazard on the grid analysis of disaster and emergency power grid construction of the platform

Zhu Youliang,Liang Wen​​​​​​​,Yang Jihai,Tao Zhenwen​​​​​​​,Ma Yong,Liu Xianming

Journal Article

Effects of galectin-3 inhibition on endometrial cell cycle and adhesion

LEI Caixia, ZHANG Wei, SUN Xiaowei, DU Guoping, WANG Li, LIU Yinkun

Journal Article

Model test study for ice force on the bank-head of the lead-navigating bank

SONG An, SUN Jinliang, LU Hai, WANG Yi′an

Journal Article

Comparison in executive function in Chinese preterm and full-term infants at eight months

Yao Feng, Hong Zhou, Yan Zhang, Anthony Perkins, Yan Wang, Jing Sun

Journal Article